May 19, 2017

Know Your Genes: FUT2 “Vitamin B12 Gene”

The FucosylTransferase 2 (FUT2) gene is associated with the synthesis of fucosyl transferase 2, an enzyme found to attach the bacterium Helicobacter pylori to the gastric […]
May 11, 2017

Know Your Genes: TMPRSS6 “Iron Gene”

Transmembrane Protease, Serine 6 (TMPRSS6) gene is associated with the synthesis of transmembrane protease, serine 6 (also known as matriptase-2), a liver serine protease. TMPRSS6 cleaves […]
May 4, 2017

Know Your Genes: GABPB1 “ The Energy Gene”

GA‐binding protein (GABP) transcription factor gene, also known as the Nuclear Respiratory Factor 2 (NRF2) gene is associated with the synthesis of GABPB1, a key transcriptional […]
May 4, 2017

Know Your Genes: TTPA “Vitamin E Gene”

The Alpha Tocopherol Transfer Protein (TTPA) gene is associated with the synthesis of alpha tocopherol transfer protein, a fat soluble anti-oxidant that is secreted by the […]
April 28, 2017

Know Your Genes: MC4R “Obesity Gene”

The Melanocortin 4 Receptor gene (MC4R) is associated with the synthesis of MC4R enzyme, a G protein coupled receptor which is found to bind to alpha […]
April 25, 2017

Know Your Genes: HLADQ “The Gluten Intolerance Gene”

The Human Leukocyte Antigen system (HLA) gene is associated with the synthesis of Major Histocompatibility Complex (MHC), which are cell surface proteins that are associated with […]
April 25, 2017

Know Your Genes: ACE “The Endurance Gene”

The Angiotensin Converting Enzyme (ACE) gene is associated with the synthesis of angiotensin converting enzyme, a key enzyme necessary to convert angiotensin I to angiotensin II. […]
April 20, 2017

Know Your Genes: LIPC “HDL Gene”

The hepatic lipase gene (LIPC) is associated with the synthesis of hepatic lipase enzyme (LIPC) which catalyzes the hydrolysis of fat. Hepatic lipase converts intermediate-density lipoprotein […]
April 19, 2017

Know Your Genes: DRD2 “Dopamine Gene”

The Dopamine Receptor Gene (DRD2) is associated with the synthesis of DRD2, which is the main receptor for all anti-psychotic drugs. The hormone Dopamine is a neurotransmitter […]
April 17, 2017

Know Your Genes: MTHFR “Folic Acid Gene”

The Methyl Tetra Hydrofolate Reductase gene (MTHFR) is associated with the synthesis of MTHFR enzyme, which converts folate obtained from the diet into an active form. […]
April 17, 2017

Know Your Genes: GC – “Vitamin D Gene”

The Group Specific Component globulin (GC) gene is associated with the synthesis of Group Specific Component globulin (GC), also called the Vitamin D Binding Protein (VDBP), […]
April 10, 2017

Know Your Genes: INSIG2 “Insulin Gene”

The Insulin signaling protein type 2 gene (INSIG2) is associated with the synthesis of INSIG2 protein which interacts with transcription factors, activating the synthesis of cholesterol […]
April 5, 2017

Know Your Genes: PPARA

The Peroxisome Proliferator- Activated Receptor (PPARA) gene is associated with the synthesis of Peroxisome Proliferator- Activated Receptor Alpha (PPARA), a protein associated with the activation of […]
March 24, 2017

Know Your Genes: MMP3 – “The Risk of Injury Gene”

The Matrix Metalloproteinase 3 (MMP3) gene is associated with the synthesis of matrix metalloproteinase 3 (also called Stromelysin-1), an enzyme which is associated with the breakdown […]
March 21, 2017

Know Your Genes: TNFA “The Inflammation Response Gene”

The Tumor Necrosis Factor Alpha (TNFA) gene is associated with the synthesis of TNFA, a pro-inflammatory cytokine that regulates immune responses such as inflammation. Specific alleles […]
March 17, 2017

Know Your Genes: CASR – “The Calcium Gene”

The Calcium sensing receptor (CASR) gene is associated with the synthesis of Calcium sensing receptor, a receptor that binds to calcium present in the blood. Specific […]
March 17, 2017

Know Your Genes: – PPARGC1A

The PPARGC1A gene is associated with the synthesis of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1a), which is associated with mitochondrial biogenesis or the production of […]
March 10, 2017

Know Your Genes: ADRB2 – “The Adrenaline Gene”

The β2 adrenergic receptor 2 (ADRB2) gene is associated with the synthesis of β2 adrenergic receptor 2, a cell membrane spanning receptor that binds to adrenaline. […]
March 8, 2017

Know Your Genes: VEGFA – “The New Blood Vessel Growth Gene”

The Vascular Endothelial Growth Factor (VEGFA) gene is associated with the synthesis VEGFA, a molecule associated with the formation of new blood vessels (angiogenesis) upon training. […]
March 6, 2017

Know Your Genes: NOS3 – “The Nitric Oxide Gene”

The Nitric Oxide Synthase 3 (NOS3) gene is associated with the synthesis of endothelial nitric oxide synthase (eNOS), an enzyme which facilitates the production of Nitric […]
March 2, 2017

Know Your Genes: MCM6 – “The Lactose Intolerance Gene”

The MCM6 gene controls the Lactase producing gene (LCT). Lactase is necessary to digest the sugar Lactose found in milk. Individuals whose body cannot produce Lactase […]
March 2, 2017

Know Your Genes: MCT1 – “The Muscle Fatigue Gene”

The MCT1 gene is associated with the synthesis of MCT1, a molecule that transports lactic acid across the muscle cell membrane. Specific alleles of this gene […]
February 27, 2017

Know Your Genes: ACTN3- “The Speed Gene”

The skeletal muscle consists of two types of fibres – fast twitch and slow twitch. The slow twitch fibres work efficiently for a long period of […]
February 25, 2017

Genetics is a Risk Factor for Osteoporosis

Osteoporosis, a bone disease affecting seniors and menopausal women is a growing concern causing over 8.9 million fractures each year worldwide (Johnell et al, 2006). In […]
February 23, 2017

Know your genes: COL5A1-“The Flexibility Gene”

The COL5A1 gene is associated with the synthesis of type V collagen, a key constituent of ligaments and tendons. Specific alleles of this gene are known […]
January 24, 2017

What regulates Energy Intake and Why Does it Differ from Person to Person?

A healthy weight is maintained during a state of energy balance- when the energy intake of an individual matches the energy expenditure. Weight can accrue over […]
December 30, 2016

A genetic explanation for why people have different taste preferences

Human sense of sight, smell, heat and taste are enabled by biological sensors in various organs. As an example, sense of sight requires vision sensors in […]
December 28, 2016

World Stroke Day 2016 “Face the Facts: Stroke is Treatable”

According to World Health Organization, an estimated 17 million people suffered from stroke in 2010 and 33 million survived after a stroke. In India, its estimated […]
December 27, 2016

Saturated Fat consumption and the APOA2 gene

There seems to be an endless debate about whether saturated fats are good or bad for your health. The truth is, it depends on your genes. […]
December 22, 2016

Do you have the ‘Obese Gene’?

Weight loss struggles are an increasing phenomenon world over with the majority of people aspiring to achieve a slim body either for aesthetic reasons or good […]
December 21, 2016

World Osteoporosis Day 2016- Osteoporosis could be linked to Gluten Intolerance

  Osteoporosis is a condition in which the bone mass is lowered, resulting in weak bones that are prone to fractures. This condition is often associated […]
December 20, 2016

How much of body weight is determined by genetics?

Anywhere between 30 to 70% of our body weight  is influenced by our genes.  And the tendency to be obese is quite common among humans, as […]
December 18, 2016

Drinking 2 or more sugary drinks per day doubles diabetes risk

 There are over 69.2 million diabetics in India with the numbers continuing to rise.  A Study found that drinking more than 2 sugary drinks per day […]
December 11, 2016

World Diabetes day 2016- November 14th

Diabetes mellitus, commonly known as diabetes, is a metabolic disease which is characterized by high blood sugar levels. This is due to either low amount of […]
December 9, 2016

Cardiovascular Disease and MTHFR gene

Cardiovascular disease is a group of diseases that involve the heart and the blood vessels. There are a number of risk factors associated with this condition, […]
December 5, 2016

Does your child complain of stomach pain after drinking milk? 3 out of 4 Indians are lactose intolerant

A common scenario witnessed in almost every household is a mother running behind her child with a glass of milk. Continuing since generations, this tug of […]
December 5, 2016

Over 10% Indians suffer from gluten intolerance. Are you one of them?

Living in India, almost every household has a high consumption of wheat. A sandwich for breakfast with chapattis for lunch and dinner seems to be the […]
December 2, 2016

Muscle fatigue and MCT1 gene

The onset of muscle fatigue has hampered many athletes from achieving their maximum potential. Lactic acid buildup is a byproduct of anaerobic metabolism. Under normal activity […]
November 22, 2016

Here is how Nitric Oxide Supplements and Nitric Oxide gene influence exercise performance

Increasing nitric oxide (NO) has become the new secret weapon for athletes and bodybuilders. It is used as the primary ingredient in various dietary supplements to […]
November 12, 2016

Top 10 Tips to Prevent Diabetes in India

Start early – get your diabetes risk evaluated Indians have a higher genetic risk of diabetes – get a genetic assessment , if possible Exercise and diet are […]
November 12, 2016

Top 10 facts about Diabetes

  India is the diabetes capital of the world- India has more diabetics than any other nation India is projected to have more than 10 crore […]
November 8, 2016

Are antioxidants more important for people carrying certain genes?

The World Health Organization recommends a daily intake of at least 400 grams (or five daily servings with an average serving size of 80 gms) of […]
October 31, 2016

Alert: 8 out 10 Indians are vitamin B12 deficient- Vegetarianism and genes may influence B12 levels.

In India, 60-70% of the population is believed to have lower vitamin B12 blood levels, with nearly 80% of urban middle class having this deficiency. Low […]
October 29, 2016

Dr. David Davidson talks use of personalized medicine in cardiology

Dr. David Davidson from NorthShore University HealthSystem joins the set at FOX 32 Chicago to talk about the development of personalized medicine in cardiology.
October 25, 2016

Genes & calcium requirements: Achieving the right balance

Too much calcium can hurt you! Too much calcium in your blood can weaken youar bones, create kidney stones, and interfere with the way your heart […]
October 20, 2016

US FDA revises its black box warning on Plavix (Clopidogrel)

The Food and Drug Administration (FDA) has made several changes to the prescribing information for Plavix (clopidogrel bisulfate tablets; Bristol-Myers Squibb and Sanofi). The updated box […]
October 18, 2016

Genes can Influence your Vitamin A requirement- Here’s how

According to American Heart Association (2015), cardiovascular disease is the leading global cause of death, accounting for 17.3 million deaths per year, a number that is […]
October 4, 2016

An amla (gooseberry) a day keeps the doctor away!

Eating foods high in vitamin C helps protect your heart! Cardiovascular diseases (CVDs), which includes heart diseases like coronary heart disease, heart attack, angina and stroke, […]
September 27, 2016

What do genes tell us about vitamin D requirements?

Vitamin D and health Vitamin D is a hot topic these days. We get it from the sun, fortified milk, butter, ghee, soybeans, soy milk, cheese, […]
September 24, 2016

Dr. Pitchappan’s perspective on Personalized Medicine

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