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Know your genes and achieve peak fitness

Modern sedentary lifestyle has now made obesity, a national epidemic. Doctors, nutritionists, and fitness professionals are doing everything they can to encourage people to lead healthier lives.

Why do some people respond to an aerobic workout routine by becoming incredibly fit, whereas others who exercise just as hard for months end up no fitter than when they began?

This question has bothered countless people who’ve started exercise programs and has also motivated a major study – “genetics of fitness”. Scientists have long known that when a group of people follow the same aerobic workout routine-some increase their cardiorespiratory fitness substantially, unfortunately other seem to get no benefit at all.

But what is it, that makes one person’s body receptive to exercise and another’s resistant? According to the above mentioned study, which will soon be published in The Journal of Applied Physiology, “part of the answer may depend on the state of specific genes”.

There is no magic workout that works for everybody. Customization is the key, and over the years it is being commonly used in various fields.


The latest approach for fitness, Exercise for your phenotype by knowing your genotype


If healthcare and fitness professionals know a person’s genetic predispositions they can recommend a tailor-made exercise regimen that can maximize results.

By testing specific markers, researchers have discovered that certain traits such as stamina, muscle building, fat burning, energy distribution, etc. are governed by genetics, not effort.

At first, this may sound disappointing as it demonstrates that despite the efforts, some exercises simply do not benefit everyone equally. Instead, this science clearly casts a light on what people should be doing to maximize their own unique fitness.

For example, the ACTN3 gene is responsible for the development of fast-twitch muscle fibre. Determining whether someone is better suited towards sprinting-based activities (i.e. short distance running) or endurance-based exercises (i.e. long distance running) is based on variations in this gene.

This drives home the point that genes can have profound effects on your health and body, even deep within your cells. By knowing your genes, altering your exercise pattern can lead to better fitness conditions.



Xcode is a pioneer in personal genomics, focussed on enabling personalized preventive healthcare. We are dedicated to empowering physicians, wellness professionals and customers with the most validated, accurate and actionable genomic information to positively impact and improve their client’s health and quality of life.

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