A research study on the data from Adolescent Brain Cognitive Development (ABCD) Study suggests a relationship between certain regions in the brain and weight gain among children and adolescents. The study explored the relationship between “reward region” and food processing and suggests that this region may predict obesity in children. 

Childhood obesity is a serious problem in the United States, putting children and adolescents at risk for poor health. Overweight children are much more likely to become overweight adults unless they adopt and maintain healthier patterns of eating and exercise.

Previous research has identified a region in the brain associated with overeating or unhealthy eating behavior.

The Reward System Region In The Brain

Almost all our actions are driven by two things: Necessity and Reward. An activity can be considered a reward when it motivates us or gives us pleasure. Neurons, the brain's fundamental working unit, communicates this "reward" using dopamine, which is popularly known as the "happy hormone." 

Incidentally, food-reward is common in animal training routines. An animal is rewarded with a treat when it performs certain actions and this programming of food-reward is routinely used by animal trainers in zoos and entertainment venues and other animal training facilities.

Hedonic Hunger

Hedonic hunger describes eating for pleasure than hunger - to enjoy the taste rather than to meet the body's energy needs. This pleasure eating triggers the brain's reward system region, which can lead to overeating - a common cause of obesity.

The Study

"The ABCD study or the Adolescent Brain Cognitive Development Study is the largest long-term study of brain development and child health in the United States." The study was done on over 10,000 children from ages 9-10 and was followed up through early adulthood. 

Using the data from this study, the researchers attempted to investigate the relationship between the reward system region in the brain (called the nucleus accumbens) and eating behavior by examining 5300 research participants.

It was observed that when 2000 participants returned for a one year follow up, the waist circumference had increased by an average of 2.76 centimeters per participant.

The cell density (number of cells for a given area) in the reward region of the brain was examined using a noninvasive MRI technique. 

The MRI revealed changes in the cell density that reflected the increase observed in the waist circumference. 

The study speculates that the increase in this cell density can be because of an inflammation caused due to a diet rich in high-fat foods. 

The findings essentially tell us that a vicious cycle of pleasure eating leading to changes in brain, in turn leading to overeating and increasing the risk of obesity.

Not all children who carry a few extra pounds can be classified as obese. Weight fluctuations are commonly observed in the growing stage of children. Before you decide on dietary changes for your child based on any weight gain you see, it's best to consult a doctor. The doctor may use growth charts, calculate the BMI and, take a family history, and, if necessary, may order a few tests to outline the issue behind the weight gain. 

References

  1. https://www.sciencedaily.com/releases/2012/05/120503103446.htm
  2. https://en.wikipedia.org/wiki/Dopamine
  3. https://abcdstudy.org/about/

Stroke

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Stroke, a medical condition is characterized by rapid loss of brain function due to a disturbance in the blood supply to the brain. Stroke is sometimes called a “brain attack.” If blood flow is stopped for longer than a few seconds, the brain cannot get the required oxygen and nutrients through blood and eventually brain cells can die, causing permanent damage.

Sometimes referred to as cerebrovascular accident (CVA), stroke cause rapid loss of brain function due to a disturbance in the blood supply to the brain. This can be due to ischemia (lack of blood flow) caused by blockage (thrombosis, arterial embolism), or a hemorrhage (internal bleeding or loss of blood that occurs from the vascular system into a body cavity). As a result, the affected area of the brain cannot function, which might result in an inability to move one or more limbs on one side of the body, inability to understand or formulate speech, or an inability to see one side of the visual field. A stroke is a medical emergency and if untreated, it can cause permanent neurological damage and death.

Symptoms

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Gene Involved

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Genes that have a vital role in regulating the blood & oxygen supply to the brain through formation & disruption of an atherosclerotic plaque are analyzed for variations which when present, imply that a person has increased risk for stroke.

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