The Angiotensinogen (AGT) gene is associated with the synthesis of angiotensinogen, a part of the renin-angiotensin system and a precursor to the hormone angiotensin II. Angiotensin is shown to be associated with narrowing of the blood vessels which may increase blood pressure. Angiotensinogen is also associated with the production of aldosterone, which is associated with the absorption of salt and water in the kidneys.
People with certain variants of this gene are associated with increased production of angiotensinogen, which makes them salt sensitive, with increased retention of sodium in the blood.
[Limitation]Greater increase in blood pressure on a high salt intake
Intermediate response to salt intake and blood pressure
[Advantage]Normal Salt Sensitivity
[Advantage]No significant increase in blood pressure in response to high salt diet
“Nutrigenetics, fitness genetics, health genetics are all nascent but rapidly growing areas within human genetics. The information provided herein is based on preliminary scientific studies and it is to be read and understood in that context.”