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MTHFR and Methylation

The methylenetetrahydrofolate reductase (MTHFR) mutation report provides information about the common polymorphisms in the MTHFR gene, which are associated with increased homocysteine levels in the blood.

There are two important MTHFR SNPs, rs1801133 (C677T) and rs1801131 (A1298C), associated with the MTHFR enzyme activity. These variations affect approximately 1 in 4 people significantly and about 1 in 2 people mildly.

Apart from the two important MTHFR SNPs, other variations in the MTHFR gene are associated, in varying degrees, with MTHFR enzyme activity.

The MTHFR and Methylation Report profiles 15 methylation genes and the associated SNPs, along with the health implications of the mutations and recommendations.
Price: Rs. 3500

MTHFR Sample Report Walk-Through

Traits and Details


The Methylation report gives the status of the single nucleotide polymorphism (SNP) variants for more than 15 genes that have been found to influence the methylation pathway. MTHFR is the most important enzyme in the methylation pathway. The MTHFR gene status influences the MTHFR enzyme activity and consequently its effect on the methylation pathway

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