Hydroxychloroquine: An Introduction Hydroxychloroquine is a derivative of chloroquine that has both anti-inflammatory and antimalarial activities. It is also used as an antirheumatic agent (used to treat joint pain) in systemic lupus erythematosus and rheumatoid arthritis. The exact mechanism of hydroxychloroquine action is unknown. It has been documented that its activity hampers the parasite’s ability […]
Drug Response And COVID-19 Various existing drugs are being explored in clinical trials for their potential against COVID-19, including Hydroxychloroquine, Lopinavir/ Ritonavir, and VPM1002 (recombinant BCG vaccine). So far, a newly developed antiviral called Remdesivir is the only drug approved worldwide to treat COVID-19 patients. Certain genetic variations can affect the metabolism, efficacy, and side […]
Dexamethasone: An Introduction Dexamethasone is a corticosteroid medication used for rheumatic disease, skin infections, hypersensitivity reactions, eye infections, ulcerative colitis, and chronic obstructive pulmonary disorder. Dexamethasone is a glucocorticoid. Glucocorticoids act as an anti-inflammatory drug. The National Health Service in the UK and the National Institutes of Health (NIH) in the US recommend dexamethasone for […]
Coronavirus disease 2019 (COVID-19) is a highly contagious, potentially fatal respiratory illness caused by a coronavirus (SARS-CoV). It was first identified in Wuhan, China, in December 2019, and later it rapidly spread across the world. On March 11, 2020, the World Health Organization (WHO) declared COVID-19 as a pandemic disease. How is COVID-19 Transmitted? COVID-19 […]
Gut Microbium: An Introduction The human body’s largest microorganism population resides in the intestine and is collectively called the gut microbiota/microbiome. Every individual’s microbiome is unique and is influenced by genetic, environmental, or lifestyle factors. The gut microbiome contains a complex community of microbes that live within the gastrointestinal (GI) tract, and many of these […]
Lopinavir and Ritonavir: An Introduction Lopinavir and Ritonavir are a combination of antiviral medicines used to treat human immunodeficiency virus (HIV) infection. They belong to a class of medications called protease inhibitors, which functions by decreasing the amount of HIV in the blood. When taken together, ritonavir also helps increase the amount of lopinavir in […]
What is Glucose Response? Glucose response or glucose tolerance is a measure of how fast your body can push glucose from the blood into the muscles and tissues. It is the ability to move glucose load. Your glucose tolerance can be determined by a glucose tolerance test, which is also used for diabetes diagnosis. The […]
What Is Pain Tolerance? Pain is defined as an uncomfortable feeling in response to intense or damaging stimuli. An external stimulus like the pricking of skin, heat, or pressure is detected by the pain receptors. The pain receptors activate the nerve fibers nearby. The nerve fibers send signals through the spinal cord to the brainstem. […]
What Is Blood Pressure? When blood flows through your arteries, the force that it exerts against the wall of the arteries is measured as blood pressure. It can also be understood as the resistance offered by the blood vessels to the flow of blood. Blood pressure also takes into account the amount of blood that […]
What Are Triglycerides? Triglycerides are types of fat that are commonly found in the human body. The name ‘triglyceride’ means a combination of three kinds of fats combined with a form of glucose called glycerol. The three kinds of fats are - unsaturated fats, saturated fats, and a combination of both. Triglycerides are majorly present […]
